|
N-benzyl-4-(5-bromo-1H-indol-3-yl)pyrimidin-2-amine |
|
Mycobacterium Staphylococcus |
Biofilm Biofilm |
Preclinical (in vitro) Preclinical (in vitro) |
Huggins WM, et al. 2018. ACS Med Chem Lett; Zeiler MJ, et al. 2020. ChemMedChem; Brackett SM, et al. 2020. RSC Med Chem
|
|
Compound 7 (internal name in literature) |
Depiction based on curated SMILES
HO
O
H
3
C
N
|
Vibrio |
TCP (Toxin-coregulated pilus) |
Preclinical (in vitro) |
Woodbrey AK, et al. 2018. Biochemistry |
|
Compound 13 (internal name in literature) |
Depiction based on curated SMILES
OH
O
H
3
C
N
H
|
Vibrio |
TCP (Toxin-coregulated pilus) |
Preclinical (in vitro) |
Woodbrey AK, et al. 2018. Biochemistry |
|
5-({1-[(2-chloro-1,3-thiazol-5-yl)methyl]-1H-indol-3-yl}methylene)-1,3-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione |
Depiction based on curated SMILES
Cl
O
CH
3
N
O
S
H
3
C
N
N
O
N
|
Yersinia |
TTSS secreted effectors |
Preclinical (in vitro) |
Hu X, et al. 2013. Bioorg Med Chem Lett |
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