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Compound category: Isoquinolones and derivatives
(total 3 related compounds in database)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
7-[4-[(R)-hydroxy-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]-3-methylphenyl]-2H-isoquinolin-1-one Depiction based on curated SMILES HO OH OH OH O HO H CH 3 O N H Escherichia Type 1 fimbriae Preclinical (in vivo) Mydock-McGrane L, et al. 2016. J Med Chem
7-[4-[(R)-hydroxy-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]-3-methylphenyl]-3,4-dihydro-2H-isoquinolin-1-one Depiction based on curated SMILES HO OH OH OH O HO H CH 3 O N H Escherichia Type 1 fimbriae Preclinical (in vivo) Mydock-McGrane L, et al. 2016. J Med Chem
Virstatin Depiction based on curated SMILES O HO O N O Acinetobacter
Vibrio		 TFP (Type IV pili)
TCP (Toxin-coregulated pilus)		 Preclinical (in vitro)
Preclinical (in vivo)		 Nait Chabane Y, et al. 2014. BMC Microbiol
Hung DT, et al. 2005. Science
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   


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