Drug details:
Molecular formula: C₁₆H₁₃NO₄

Standard name: 4-(1,3-dioxobenzo[de]isoquinolin-2-yl)butanoic acid

Synonyms:

1,3-Dioxo-1H-benz(de)isoquinoline-2(3H)-butanoic acid 1,3-Dioxo-1H-benz(de)isoquinoline-2(3H)-butyric acid 1,3-dioxo-1H-Benz[de]isoquinoline-2(3H)-butanoic acid 1h,3H-benzo(de)isoquinoline-2-butyric acid-1,3-dione 1H-Benz(de)isoquinoline-2(3H)-butanoic acid, 1,3-dioxo- 4-(1,3-DIOXO-1H,3H-BENZO(DE)ISOQUINOLIN-2-YL)-BUTYRIC ACID 4-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-butyric acid 4-(1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)butanoic acid 4-(1,3-dioxobenzo[de]isoquinolin-2-yl)butanoic acid ......

Curated SMILES: C1=CC2=C3C(=C1)C(=O)N(C(=O)C3=CC=C2)CCCC(=O)O

Evidence for compound's anti-virulence activity:

Acinetobacter
Related VF: TFP (Type IV pili)
Target: Not determined
Drug effect: Acts on type IV pili biogensis.
Max phase: Preclinical (in vitro)
Publication:
Nait Chabane Y, et al., 2014. Virstatin inhibits biofilm formation and motility of Acinetobacter baumannii. BMC Microbiol 14:62.

Vibrio
Related VF: TCP (Toxin-coregulated pilus)
Target: TcpN/ToxT
Drug effect: Inhibits the dimerization of the transcriptional activator ToxT thus to prevent expression of two critical V. cholerae virulence factors, CT and the TCP.
Max phase: Preclinical (in vivo)
Publication:
Hung DT, et al., 2005. Small-molecule inhibitor of Vibrio cholerae virulence and intestinal colonization. Science 310(5748):670-4.