|
(2R,3R)-2-[[3-(2-chlorophenyl)phenyl]sulfonylamino]-N-hydroxy-3-methylpentanamide |
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Thompson JC, et al. 2020. Bioorg Med Chem |
|
(2S,3S)-2-[[3-(2,4-dichlorophenyl)phenyl]sulfonylamino]-N-hydroxy-3-methylpentanamide |
Depiction based on curated SMILES
OH
N
H
O
Cl
Cl
H
3
C
O
O
S
HN
CH
3
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Thompson JC, et al. 2020. Bioorg Med Chem |
|
(2S,3S)-2-[[3-(2,5-dichlorophenyl)phenyl]sulfonylamino]-N-hydroxy-3-methylpentanamide |
Depiction based on curated SMILES
OH
N
H
O
Cl
Cl
H
3
C
O
O
S
HN
CH
3
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Thompson JC, et al. 2020. Bioorg Med Chem |
|
(2S,3S)-2-[[3-(2,6-dichlorophenyl)phenyl]sulfonylamino]-N-hydroxy-3-methylpentanamide |
Depiction based on curated SMILES
OH
N
H
O
Cl
Cl
H
3
C
O
O
S
HN
CH
3
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Thompson JC, et al. 2020. Bioorg Med Chem |
|
(2S,3S)-2-[[3-(2-chlorophenyl)phenyl]sulfonylamino]-N-hydroxy-3-methylpentanamide |
Depiction based on curated SMILES
OH
N
H
O
Cl
H
3
C
O
O
S
HN
CH
3
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Thompson JC, et al. 2020. Bioorg Med Chem |
|
(2S,3S)-2-[[3-(3,4-dichlorophenyl)phenyl]sulfonylamino]-N-hydroxy-3-methylpentanamide |
Depiction based on curated SMILES
OH
N
H
O
Cl
Cl
H
3
C
O
O
S
HN
CH
3
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Thompson JC, et al. 2020. Bioorg Med Chem |
|
(2S,3S)-2-[[3-(3-chlorophenyl)phenyl]sulfonylamino]-N-hydroxy-3-methylpentanamide |
Depiction based on curated SMILES
OH
N
H
O
Cl
H
3
C
O
O
S
HN
CH
3
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Thompson JC, et al. 2020. Bioorg Med Chem |
|
(2S,3S)-2-[[3-(furan-2-yl)phenyl]sulfonylamino]-N-hydroxy-3-methylpentanamide |
Depiction based on curated SMILES
OH
N
H
O
O
H
3
C
O
O
S
N
H
H
3
C
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Thompson JC, et al. 2020. Bioorg Med Chem |
|
(2S,3S)-2-[[3-(furan-3-yl)phenyl]sulfonylamino]-N-hydroxy-3-methylpentanamide |
Depiction based on curated SMILES
OH
N
H
O
O
H
3
C
O
O
S
N
H
H
3
C
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Thompson JC, et al. 2020. Bioorg Med Chem |
|
(2S,3S)-N-hydroxy-3-methyl-2-[[3-(3-nitrophenyl)phenyl]sulfonylamino]pentanamide |
Depiction based on curated SMILES
OH
HN
O
_
O
O
+
N
CH
3
O
O
S
N
H
H
3
C
|
Clostridium |
BoNT (Botulinum neurotoxin) |
Preclinical (in vitro) |
Thompson JC, et al. 2020. Bioorg Med Chem |
|
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