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Compound category: Organic acids and derivatives
(total 132 related compounds in database, current show from 91 to 100)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
1-[3-(Trifluoromethyl)benzyl]-5-nitro-3'-(3,4-difluorophenyl)spiro[1H-indole-3(2H),2'-thiazolidine]-2,4'-dione 1',1'-dioxide Depiction based on curated SMILES + N O _ O F N F F S O O O N O F F Mycobacterium Exoenzyme Preclinical (in vitro) Vintonyak VV, et al. 2010. Angew Chem Int Ed Engl
3'-(3-Chloro-4-fluorophenyl)-1-(3,4-difluorobenzyl)-5-nitro-4'H-spiro[indole-3,2'-[1,3]thiazolidine]-2,4'(1H)-dione 1',1'-dioxide Depiction based on curated SMILES N + N O _ O Cl F N S O O O O F F Mycobacterium Exoenzyme Preclinical (in vitro) Vintonyak VV, et al. 2010. Angew Chem Int Ed Engl
1-(3-Chlorobenzyl)-3'-(3-chloro-4-fluorophenyl)-5-nitro-4'H-spiro[indole-3,2'-[1,3]thiazolidine]-2,4'(1H)-dione 1',1'-dioxide Depiction based on curated SMILES N + N O _ O Cl F N S O O O O Cl Mycobacterium Exoenzyme Preclinical (in vitro) Vintonyak VV, et al. 2010. Angew Chem Int Ed Engl
1-(4-Chlorobenzyl)-3'-(3-chloro-4-fluorophenyl)-5-nitro-4'H-spiro[indole-3,2'-[1,3]thiazolidine]-2,4'(1H)-dione 1',1'-dioxide Depiction based on curated SMILES N + N O _ O Cl F N S O O O O Cl Mycobacterium Exoenzyme Preclinical (in vitro) Vintonyak VV, et al. 2010. Angew Chem Int Ed Engl
3'-(3-Chloro-4-fluorophenyl)-5-nitro-1-[3-(trifluoromethyl)benzyl]-4'H-spiro[indole-3,2'-[1,3]thiazolidine]-2,4'(1H)-dione 1',1'-dioxide Depiction based on curated SMILES + N O _ O F N Cl F S O O O N O F F Mycobacterium Exoenzyme Preclinical (in vitro) Vintonyak VV, et al. 2010. Angew Chem Int Ed Engl
ZTB23(R) Depiction based on curated SMILES O S S HO O N HO O H Mycobacterium Exoenzyme Preclinical (in vitro) Mori M, et al. 2014. Bioorg Med Chem Lett
4-[[3-(3,4-difluorophenyl)-5'-nitro-1,1,2',4-tetraoxo-spiro[1,3-thiazolidine-2,3'-indoline]-1'-yl]methyl]benzonitrile Depiction based on curated SMILES N F F O S O O O N N + N O _ O Mycobacterium Exoenzyme Preclinical (in vitro) Vintonyak VV, et al. 2010. Angew Chem Int Ed Engl
N-[(Z)-(2-hydroxy-3-prop-2-enylphenyl)methylideneamino]-4,5,6,7-tetrahydro-1H-indazole-3-carboxamide Depiction based on curated SMILES N H N CH 2 O N H N HO Mycobacterium Motility Preclinical (in vitro) Ouertatani-Sakouhi H, et al. 2017. PLoS One
2-(pyridin-3-ylcarbonylamino)ethyl (2~{S})-1-(phenylmethyl)sulfonylpiperidine-2-carboxylate Depiction based on curated SMILES O O S N O NH O O N Burkholderia
Neisseria
Others
Others
Preclinical (in vitro)
Preclinical (in vitro)
Iwasaki J, et al. 2022. J Antimicrob Chemother
2-{[3,5-bis(2-methoxyethoxy)benzene-1-carbonyl]amino}ethyl (2S)-1-(benzylsulfonyl)piperidine-2-carboxylate Depiction based on curated SMILES N S O O O O CH 3 O O H 3 C O N H O O Burkholderia
Neisseria
Others
Others
Preclinical (in vitro)
Preclinical (in vitro)
Iwasaki J, et al. 2022. J Antimicrob Chemother
   


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