|
1-[3-(Trifluoromethyl)benzyl]-5-nitro-3'-(3,4-difluorophenyl)spiro[1H-indole-3(2H),2'-thiazolidine]-2,4'-dione 1',1'-dioxide |
|
Mycobacterium |
Exoenzyme |
Preclinical (in vitro) |
Vintonyak VV, et al. 2010. Angew Chem Int Ed Engl |
|
3'-(3-Chloro-4-fluorophenyl)-1-(3,4-difluorobenzyl)-5-nitro-4'H-spiro[indole-3,2'-[1,3]thiazolidine]-2,4'(1H)-dione 1',1'-dioxide |
Depiction based on curated SMILES
N
+
N
O
_
O
Cl
F
N
S
O
O
O
O
F
F
|
Mycobacterium |
Exoenzyme |
Preclinical (in vitro) |
Vintonyak VV, et al. 2010. Angew Chem Int Ed Engl |
|
1-(3-Chlorobenzyl)-3'-(3-chloro-4-fluorophenyl)-5-nitro-4'H-spiro[indole-3,2'-[1,3]thiazolidine]-2,4'(1H)-dione 1',1'-dioxide |
Depiction based on curated SMILES
N
+
N
O
_
O
Cl
F
N
S
O
O
O
O
Cl
|
Mycobacterium |
Exoenzyme |
Preclinical (in vitro) |
Vintonyak VV, et al. 2010. Angew Chem Int Ed Engl |
|
1-(4-Chlorobenzyl)-3'-(3-chloro-4-fluorophenyl)-5-nitro-4'H-spiro[indole-3,2'-[1,3]thiazolidine]-2,4'(1H)-dione 1',1'-dioxide |
Depiction based on curated SMILES
N
+
N
O
_
O
Cl
F
N
S
O
O
O
O
Cl
|
Mycobacterium |
Exoenzyme |
Preclinical (in vitro) |
Vintonyak VV, et al. 2010. Angew Chem Int Ed Engl |
|
3'-(3-Chloro-4-fluorophenyl)-5-nitro-1-[3-(trifluoromethyl)benzyl]-4'H-spiro[indole-3,2'-[1,3]thiazolidine]-2,4'(1H)-dione 1',1'-dioxide |
Depiction based on curated SMILES
+
N
O
_
O
F
N
Cl
F
S
O
O
O
N
O
F
F
|
Mycobacterium |
Exoenzyme |
Preclinical (in vitro) |
Vintonyak VV, et al. 2010. Angew Chem Int Ed Engl |
|
ZTB23(R) |
Depiction based on curated SMILES
O
S
S
HO
O
N
HO
O
H
|
Mycobacterium |
Exoenzyme |
Preclinical (in vitro) |
Mori M, et al. 2014. Bioorg Med Chem Lett |
|
4-[[3-(3,4-difluorophenyl)-5'-nitro-1,1,2',4-tetraoxo-spiro[1,3-thiazolidine-2,3'-indoline]-1'-yl]methyl]benzonitrile |
Depiction based on curated SMILES
N
F
F
O
S
O
O
O
N
N
+
N
O
_
O
|
Mycobacterium |
Exoenzyme |
Preclinical (in vitro) |
Vintonyak VV, et al. 2010. Angew Chem Int Ed Engl |
|
N-[(Z)-(2-hydroxy-3-prop-2-enylphenyl)methylideneamino]-4,5,6,7-tetrahydro-1H-indazole-3-carboxamide |
Depiction based on curated SMILES
N
H
N
CH
2
O
N
H
N
HO
|
Mycobacterium |
Motility |
Preclinical (in vitro) |
Ouertatani-Sakouhi H, et al. 2017. PLoS One |
|
2-(pyridin-3-ylcarbonylamino)ethyl (2~{S})-1-(phenylmethyl)sulfonylpiperidine-2-carboxylate |
Depiction based on curated SMILES
O
O
S
N
O
NH
O
O
N
|
Burkholderia Neisseria |
Others Others |
Preclinical (in vitro) Preclinical (in vitro) |
Iwasaki J, et al. 2022. J Antimicrob Chemother
|
|
2-{[3,5-bis(2-methoxyethoxy)benzene-1-carbonyl]amino}ethyl (2S)-1-(benzylsulfonyl)piperidine-2-carboxylate |
Depiction based on curated SMILES
N
S
O
O
O
O
CH
3
O
O
H
3
C
O
N
H
O
O
|
Burkholderia Neisseria |
Others Others |
Preclinical (in vitro) Preclinical (in vitro) |
Iwasaki J, et al. 2022. J Antimicrob Chemother
|
|
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