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Compound category:
Pyridines and derivatives
(total
3
related compounds in database)
Compound name
2D structure
Target pathogen(s)
Related VF/VFcategory
Max phase
Reference(s)
Fusaric acid
Depiction based on curated SMILES
H
3
C
N
O
HO
Salmonella
TTSS (SPI-1 encode)
Preclinical (
in vitro
)
Li J, et al. 2014.
Biochem Biophys Res Commun
(E)-N'-(3,5-Dibromo-2-hydroxybenzylidene)nicotinohydrazide
Depiction based on curated SMILES
N
OH
Br
O
Br
N
N
H
Chlamydia
Escherichia
Salmonella
TTSS (Type III secretion system)
TTSS (Type III secretion system)
TTSS (SPI-1 encode)
;
TTSS (SPI-2 encode)
Preclinical (
in vitro
)
Preclinical (
in vitro
)
Preclinical (
in vitro
)
Bailey L, et al. 2007.
FEBS Lett
Tree JJ, et al. 2009.
Infect Immun
;
Wang D, et al. 2011.
J Biol Chem
Negrea A, et al. 2007.
Antimicrob Agents Chemother
Nicotinic acid (5-bromo-2-hydroxy-benzylidene)-hydrazide
Depiction based on curated SMILES
N
OH
O
Br
N
N
H
Salmonella
Shigella
TTSS (SPI-1 encode)
;
TTSS (SPI-2 encode)
TTSS (Type III secretion system)
Preclinical (
in vitro
)
Preclinical (
in vitro
)
Negrea A, et al. 2007.
Antimicrob Agents Chemother
Veenendaal AK, et al. 2009.
J Bacteriol
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.
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