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Compound category:
Quinolines and derivatives
(total
3
related compounds in database)
Compound name
2D structure
Target pathogen(s)
Related VF/VFcategory
Max phase
Reference(s)
5-nitro-7-[(3-phenylpyrrolidin-1-yl)methyl]quinolin-8-ol
Depiction based on curated SMILES
N
OH
O
N
_
O
+
N
Chlamydia
Yersinia
TTSS (Type III secretion system)
TTSS (Type III secretion system)
Preclinical (
in vitro
)
Preclinical (
in vitro
)
Enquist PA, et al. 2012.
Bioorg Med Chem Lett
5-nitro-7-[(4-phenyl-1-piperazinyl)methyl]-8-quinolinol
Depiction based on curated SMILES
N
OH
O
N
N
_
O
+
N
Chlamydia
Yersinia
TTSS (Type III secretion system)
TTSS (Type III secretion system)
Preclinical (
in vitro
)
Preclinical (
in vitro
)
Enquist PA, et al. 2012.
Bioorg Med Chem Lett
7-[[4-(4-fluorophenyl)piperazin-1-yl]methyl]-5-nitroquinolin-8-ol
Depiction based on curated SMILES
N
OH
F
O
N
N
_
O
+
N
Chlamydia
Yersinia
TTSS (Type III secretion system)
TTSS (Type III secretion system)
Preclinical (
in vitro
)
Preclinical (
in vitro
)
Enquist PA, et al. 2012.
Bioorg Med Chem Lett
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