Drug details:
Molecular formula: C₁₂H₁₀N₂O₅

Standard name: N-[(E)-(2,3,4-trihydroxyphenyl)methylideneamino]furan-2-carboxamide

Curated SMILES: O=C(N/N=C/C1=CC=C(O)C(O)=C1O)C1=CC=CO1

Evidence for compound's anti-virulence activity:

Salmonella
Related VF: TTSS (SPI-1 encode); TTSS (SPI-2 encode)
Target: Not determined
Drug effect: Efficiently affected SPI1 and SPI2 activity.
Max phase: Preclinical (in vitro)
Publication:
Negrea A, et al., 2007. Salicylidene acylhydrazides that affect type III protein secretion in Salmonella enterica serovar typhimurium. Antimicrob Agents Chemother 51(8):2867-76.

Shigella
Related VF: TTSS (Type III secretion system)
Target: MxiH
Drug effect: Inhibits needle assembly.
Max phase: Preclinical (in vitro)
Publication:
Veenendaal AK, et al., 2009. Small-molecule type III secretion system inhibitors block assembly of the Shigella type III secreton. J Bacteriol 191(2):563-70.