Drug details:
Molecular formula: C₂₄H₂₀N₂O₄S

Standard name: (5Z)-5-[(4-hydroxy-3,5-dimethoxyphenyl)methylidene]-3-phenyl-2-phenylimino-1,3-thiazolidin-4-one

Curated SMILES: COC1=CC(/C=C2\S/C(=N\C3=CC=CC=C3)N(C3=CC=CC=C3)C2=O)=CC(OC)=C1O

Evidence for compound's anti-virulence activity:

Salmonella
Related VF: TTSS (SPI-1 encode)
Target: May targeting secretin protein
Drug effect: Inhibits bacterial secretion systems in a wide array of animal and plant pathogens.
Max phase: Preclinical (in vitro)
Publication:
Felise HB, et al., 2008. An inhibitor of gram-negative bacterial virulence protein secretion. Cell Host Microbe 4(4):325-36.

Yersinia
Related VF: TTSS (Type III secretion system)
Target: May target the seretin protein
Drug effect: Inhibits translocation of both Yop and Ysp proteins.
Max phase: Preclinical (in vitro)
Publication:
Felise HB, et al., 2008. An inhibitor of gram-negative bacterial virulence protein secretion. Cell Host Microbe 4(4):325-36.