Drug details:
Molecular formula: C₃₀H₃₀F₃N₅O

Standard name: N-methyl-3-[1-(4-piperazin-1-ylphenyl)-5-[4-[4-(trifluoromethyl)phenyl]phenyl]pyrazol-3-yl]propanamide

Synonyms:

OSU-T315 (1,5-regioisomer) compound 22 [PMID: 21823616] N-methyl-3-[1-(4-piperazin-1-ylphenyl)-5-[4-[4-(trifluoromethyl)phenyl]phenyl]pyrazol-3-yl]propanamide ILK inhibitor 22(1,5)

Curated SMILES: CNC(=O)CCC1=NN(C2=CC=C(N3CCNCC3)C=C2)C(C2=CC=C(C3=CC=C(C(F)(F)F)C=C3)C=C2)=C1

Evidence for compound's anti-virulence activity:

Acinetobacter
Related VFcategory: Biofilm
Target: WrbA
Drug effect: Inhibits WrbA to reduce capacity to transition to a biofilm-forming lifestyle.
Max phase: Preclinical (in vitro)
Publication:
Moshiri J, et al., 2018. Identification of a Small Molecule Anti-biofilm Agent Against Salmonella enterica. Front Microbiol 9:2804.

Salmonella
Related VFcategory: Biofilm
Target: WrbA
Drug effect: Inhibits biofilm formation.
Max phase: Preclinical (in vitro)
Publication:
Moshiri J, et al., 2018. Identification of a Small Molecule Anti-biofilm Agent Against Salmonella enterica. Front Microbiol 9:2804.