Drug details:
Molecular formula: C₉H₁₀O₂

Standard name: 3,4-dimethylbenzoic acid

Synonyms:

Benzoic acid, 3,4-dimethyl- o-Xylene-4-carboxylic Acid 3,4-DiMethyl-Benzoic Acid 1-Carboxy-3,4-dimethylbenzene 3,4-Dimethylbenzoicacid EINECS 210-576-7 3,4-dimethyl benzoic acid 3, 4 dimethyl benzoic acid 4-09-00-01803 (Beilstein Handbook Reference) 3,4-Dimethylbenzoic acid, 98%

Curated SMILES: CC1=CC=C(C(=O)O)C=C1C

Evidence for compound's anti-virulence activity:

Salmonella
Related VF: TTSS (SPI-1 encode)
Target: Not determined
Drug effect: Represses the expression of hilA, the gene encoding the master regulator of invasion genes.
Max phase: Preclinical (in vitro)
Publication:
Peixoto RJM, et al., 2017. Repression of Salmonella Host Cell Invasion by Aromatic Small Molecules from the Human Fecal Metabolome. Appl Environ Microbiol 83(19):e01148-17.