Drug details:
Molecular formula: C₂₂H₃₀Cl₂N₄O₆

Standard name: 1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]anthracene-9,10-dione;dihydrochloride

Synonyms:

Mitoxantrone dihydrochloride Mitoxantrone HCl Novantrone Novantron Mitoxantrone 2HCl Mitoxantrone (dihydrochloride) Mitozantrone MITOXANTHRONE HYDROCHLORIDE mitozantrone dihydrochloride ......

Curated SMILES: C1=CC(=C2C(=C1NCCNCCO)C(=O)C3=C(C=CC(=C3C2=O)O)O)NCCNCCO.Cl.Cl

Evidence for compound's anti-virulence activity:

Salmonella
Related VFcategory: Invasion
Target: Not determined
Drug effect: Inhibits bacterial invasion and intracellular replication.
Max phase: Preclinical (in vitro)
Publication:
Ridge Y, et al., 2018. High-throughput screening of a collection of known pharmacologically active small compounds for inhibitors of Salmonella invasion and intracellular replication. J Appl Microbiol 125(3):724-730.