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Mefenamic acid

Drug details:
Molecular formula: C15H15NO2

Classification: Benzoic acids and derivatives; Benzene and substituted derivatives; Benzenoids; Organic compounds;
Synonyms:  Ponstel
Mephenamic acid
2-[(2,3-dimethylphenyl)amino]benzoic acid
2-((2,3-Dimethylphenyl)amino)benzoic acid
Mephenaminic acid
Ponstan
Parkemed
Coslan
Mefacit
......

Chemical structure:
Depiction based on curated SMILES H 3 C HO O CH 3 N H

Evidence for compound's anti-virulence activity:

Salmonella
Related VFcategory: Invasion
Target: Not determined
Drug effect: Inhibits bacterial invasion and intracellular replication.
Max phase: Preclinical (in vitro)
Publication:
Ridge Y, et al., 2018. High-throughput screening of a collection of known pharmacologically active small compounds for inhibitors of Salmonella invasion and intracellular replication. J Appl Microbiol 125(3):724-730.








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