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9-methoxy-4-{4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}-5H-pyrimido[5,4-b]indole

Drug details:
Molecular formula: C24H25N5O

Classification: Piperazines; Diazinanes; Organoheterocyclic compounds; Organic compounds;
Chemical structure:
Depiction based on curated SMILES HN N CH 3 N N N O

Evidence for compound's anti-virulence activity:

Salmonella
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits biofilm formation.
Max phase: Preclinical (in vitro)
Publication:
Robijns SC, et al., 2012. Identification and characterization of 4-[4-(3-phenyl-2-propen-1-yl)-1-piperazinyl]-5H-pyrimido[5,4-b]indole derivatives as Salmonella biofilm inhibitors. FEMS Immunol Med Microbiol 65(2):390-4.








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