Drug details:
Molecular formula: C₁₀H₉NO₂

Standard name: 2-(1H-indol-3-yl)acetic acid

Synonyms:

3-Indoleacetic acid indoleacetic acid Heteroauxin 1H-Indole-3-acetic acid 2-(1H-Indol-3-yl)acetic acid 1H-indol-3-ylacetic acid Rhizopin Rhizopon A Indol-3-ylacetic acid ......

Curated SMILES: O=C(O)CC1=CNC2=CC=CC=C12

Evidence for compound's anti-virulence activity:

Salmonella
Related VF: TTSS (SPI-1 encode)
Target: SipB/SspB
Drug effect: Interacts with the Salmonella translocon protein SipB to inhibit T3SS secretion.
Max phase: Preclinical (in vitro)
Publication:
McShan AC, et al., 2016. Characterization of the Binding of Hydroxyindole, Indoleacetic acid, and Morpholinoaniline to the Salmonella Type III Secretion System Proteins SipD and SipB. ChemMedChem 11(9):963-71.