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Compound category: Indoles and derivatives
(total 86 related compounds in database, current show from 1 to 10)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
7-hydroxyindole Depiction based on curated SMILES OH N H Pseudomonas Biofilm Preclinical (in vivo) Lee J, et al. 2009. Microb Biotechnol
Indole Depiction based on curated SMILES N H Pseudomonas Biofilm Preclinical (in vivo) Lee J, et al. 2009. Microb Biotechnol
Ellipticine hydrochloride Depiction based on curated SMILES ClH CH 3 N H CH 3 N Streptococcus Suilysin Preclinical (in vivo) Wang C, et al. 2021. Appl Environ Microbiol
Compound 8
(internal name in literature)		 Depiction based on curated SMILES HO O CH 3 N Vibrio TCP (Toxin-coregulated pilus) Preclinical (in vivo) Woodbrey AK, et al. 2018. Biochemistry
(S)-(-)-Indoline-2-carboxylic acid Depiction based on curated SMILES N H O OH Yersinia TTSS secreted effectors Preclinical (in vivo) Liang F, et al. 2003. J Biol Chem
[1-(1H-indol-3-yl)-1-oxopropan-2-yl] 2-(4-acetamidophenyl)-1,3-dioxoisoindole-5-carboxylate Depiction based on curated SMILES CH 3 O N H O O N H N CH 3 O O O Burkholderia
Yersinia		 Bsa T3SS
TTSS (Type III secretion system)		 Preclinical (in vitro)
Preclinical (in vivo)		 Swietnicki W, et al. 2011. PLoS One
Norharmane Depiction based on curated SMILES N H N Escherichia
Pseudomonas		 Biofilm
Biofilm		 Preclinical (in vivo)
Preclinical (in vitro)		 Lee JH, et al. 2017. Phytomedicine
SYG-180-2-2
(internal name in literature)		 Depiction based on curated SMILES Se O N H HN Staphylococcus β-hemolysin Preclinical (in vivo) Rao L, et al. 2021. Front Microbiol; Rao L, et al. 2022. Front Cell Infect Microbiol
5-Bromo-2-(pyridin-4-yl)-1H-indole Depiction based on curated SMILES Br N H N Acinetobacter Biofilm Preclinical (in vitro) Na SH, et al. 2021. J Microbiol
3-Indoleacrylic acid Depiction based on curated SMILES N H O HO Burkholderia Quorum-sensing Preclinical (in vitro) Christensen QH, et al. 2013. Proc Natl Acad Sci U S A
   


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