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Compound category: Indoles and derivatives
(total 86 related compounds in database, current show from 61 to 70)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
3-hydroxy-3-[2-oxo-2-(pyridin-4-yl)ethyl]-1,3-dihydro-2H-indol-2-one Depiction based on curated SMILES OH N O HN O Pseudomonas Biofilm Preclinical (in vitro) von Ambüren J, et al. 2020. Microorganisms
1H-Indole, 3-(2-pyridin-4-yl-thiazol-4-yl)- Depiction based on curated SMILES N N S HN Pseudomonas
Yersinia		 TTSS (Type III secretion system)
TTSS (Type III secretion system)		 Preclinical (in vitro)
Preclinical (in vitro)		 Harmon DE, et al. 2010. Antimicrob Agents Chemother
5-Hydroxyindole Depiction based on curated SMILES OH N H Salmonella
Shigella		 TTSS (SPI-1 encode)
TTSS (Type III secretion system)		 Preclinical (in vitro)
Preclinical (in vitro)		 McShan AC, et al. 2016. ChemMedChem
Dey S, et al. 2017. ChemMedChem
Indole-3-acetic acid Depiction based on curated SMILES O OH N H Salmonella TTSS (SPI-1 encode) Preclinical (in vitro) McShan AC, et al. 2016. ChemMedChem
Pirlindole mesylate Depiction based on curated SMILES HO O O S CH 3 CH 3 HN N Salmonella Invasion Preclinical (in vitro) Ridge Y, et al. 2018. J Appl Microbiol
4-(5-bromo-1-butylindol-3-yl)pyrimidin-2-amine Depiction based on curated SMILES N Br N NH 2 CH 3 N Staphylococcus Biofilm Preclinical (in vitro) Huggins WM, et al. 2018. ACS Med Chem Lett
4-(5-bromo-1-ethylindol-3-yl)pyrimidin-2-amine Depiction based on curated SMILES Br N NH 2 H 3 C N N Staphylococcus Biofilm Preclinical (in vitro) Huggins WM, et al. 2018. ACS Med Chem Lett
4-(5-bromo-1-propylindol-3-yl)pyrimidin-2-amine Depiction based on curated SMILES Br N NH 2 H 3 C N N Staphylococcus Biofilm Preclinical (in vitro) Huggins WM, et al. 2018. ACS Med Chem Lett
4-(5-Bromo-1H-indol-3-yl)-N,N-dimethylpyrimidin-2-amine Depiction based on curated SMILES N Br CH 3 N H N H 3 C N Staphylococcus Biofilm Preclinical (in vitro) Huggins WM, et al. 2018. ACS Med Chem Lett
4-(5-bromo-1H-indol-3-yl)-N-ethylpyrimidin-2-amine Depiction based on curated SMILES N Br H 3 C N H N NH Staphylococcus Biofilm Preclinical (in vitro) Huggins WM, et al. 2018. ACS Med Chem Lett
   


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