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Compound category: Indoles and derivatives
(total 86 related compounds in database, current show from 11 to 20)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
3-[(3-methoxyphenyl)(4-methylpiperazinyl)methyl]-2-phenylindol-1-ol Depiction based on curated SMILES OH N H 3 C CH 3 O N N Burkholderia Quorum-sensing Preclinical (in vitro) Christensen QH, et al. 2013. Proc Natl Acad Sci U S A
1-hydroxy-3-[(4-methoxyphenyl)-(4-methylpiperazin-1-yl)methyl]-2-phenylindole Depiction based on curated SMILES OH N H 3 C CH 3 O N N Burkholderia Quorum-sensing Preclinical (in vitro) Christensen QH, et al. 2013. Proc Natl Acad Sci U S A
1-hydroxy-3-[(4-methylphenyl)-(4-methylpiperazin-1-yl)methyl]-2-phenylindole Depiction based on curated SMILES OH CH 3 N N H 3 C N Burkholderia Quorum-sensing Preclinical (in vitro) Christensen QH, et al. 2013. Proc Natl Acad Sci U S A
3-[(4-methylpiperazin-1-yl)(pyridin-2-yl)methyl]-2-phenyl-1H-indol-1-ol Depiction based on curated SMILES OH N H 3 C N N N Burkholderia Quorum-sensing Preclinical (in vitro) Christensen QH, et al. 2013. Proc Natl Acad Sci U S A
4-[(1-hydroxy-2-phenylindol-3-yl)-(4-methylphenyl)methyl]morpholine Depiction based on curated SMILES O N OH H 3 C N Burkholderia Quorum-sensing Preclinical (in vitro) Christensen QH, et al. 2013. Proc Natl Acad Sci U S A
3-((4-chlorophenyl)(morpholino)methyl)-2-phenyl-1H-indol-1-ol Depiction based on curated SMILES OH N Cl N O Burkholderia Quorum-sensing Preclinical (in vitro) Christensen QH, et al. 2013. Proc Natl Acad Sci U S A
Ethyl 4-((1-hydroxy-2-phenyl-1H-indol-3-yl)(pyridin-2-yl)methyl)piperazine-1-carboxylate Depiction based on curated SMILES N HO O O N N CH 3 N Burkholderia Quorum-sensing Preclinical (in vitro) Christensen QH, et al. 2013. Proc Natl Acad Sci U S A
Roxindole Depiction based on curated SMILES OH HN N Coxiella
Legionella		 Dot/Icm T4SS
Dot/Icm (Defect in organella trafficking/intracellular multiplication)		 Preclinical (in vitro)
Preclinical (in vitro)		 Cheng E, et al. 2022. mBio
2-Chloro-4beta-(4-chlorophenyl)-3,4,6,7,12,12balpha-hexahydro-12-(2-fluorobenzoyl)indolo[2,3-a]quinolizine-6alpha-carboxylic acid Depiction based on curated SMILES N O HO F Cl H H Cl N H O Mycobacterium Exoenzyme Preclinical (in vitro) Nören-Müller A, et al. 2006. Proc Natl Acad Sci U S A
(4S,6S,12bR)-4-(4-bromophenyl)-2-chloro-12-(2,3-difluorobenzoyl)-3,4,6,7,12,12b-hexahydroindolo[2,3-a]quinolizine-6-carboxylic acid Depiction based on curated SMILES O F F O HO Br H H N H Cl N Mycobacterium Exoenzyme Preclinical (in vitro) Nören-Müller A, et al. 2006. Proc Natl Acad Sci U S A
   


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