Drug details:
Molecular formula: C₂₉H₂₀BrClF₂N₂O₃

Standard name: (4S,6S,12bR)-4-(4-bromophenyl)-2-chloro-12-(2,3-difluorobenzoyl)-4,6,7,12b-tetrahydro-3H-indolo[2,3-a]quinolizine-6-carboxylic acid

Curated SMILES: C1[C@H](N2[C@@H](CC3=C([C@H]2C=C1Cl)N(C4=CC=CC=C34)C(=O)C5=C(C(=CC=C5)F)F)C(=O)O)C6=CC=C(C=C6)Br

Evidence for compound's anti-virulence activity:

Mycobacterium
Related VFcategory: Exoenzyme
Target: PtpB
Drug effect: Inhibits protein tyrosine phosphatase B (PtpB) to interfere with signal transduction pathways in macrophages.
Max phase: Preclinical (in vitro)
Publication:
Nören-Müller A, et al., 2006. Discovery of protein phosphatase inhibitor classes by biology-oriented synthesis. Proc Natl Acad Sci U S A 103(28):10606-11.