Drug details:
Molecular formula: C₂₉H₂₁Cl₂FN₂O₃

Standard name: (4S,6S,12bR)-2-chloro-4-(4-chlorophenyl)-12-(2-fluorobenzoyl)-4,6,7,12b-tetrahydro-3H-indolo[2,3-a]quinolizine-6-carboxylic acid

Curated SMILES: [H][C@]12C=C(Cl)C[C@@H](C3=CC=C(Cl)C=C3)N1[C@H](C(=O)O)CC1=C2N(C(=O)C2=CC=CC=C2F)C2=C1C=CC=C2

Evidence for compound's anti-virulence activity:

Mycobacterium
Related VFcategory: Exoenzyme
Target: PtpB
Drug effect: Inhibits protein tyrosine phosphatase B (PtpB) to interfere with signal transduction pathways in macrophages.
Max phase: Preclinical (in vitro)
Publication:
Nören-Müller A, et al., 2006. Discovery of protein phosphatase inhibitor classes by biology-oriented synthesis. Proc Natl Acad Sci U S A 103(28):10606-11.