Drug details:
Molecular formula: C₂₇H₂₉N₃O₂

Standard name: 1-hydroxy-3-[(3-methoxyphenyl)-(4-methylpiperazin-1-yl)methyl]-2-phenylindole

Curated SMILES: CN1CCN(CC1)C(C2=CC(=CC=C2)OC)C3=C(N(C4=CC=CC=C43)O)C5=CC=CC=C5

Evidence for compound's anti-virulence activity:

Burkholderia
Related VF: Quorum-sensing
Target: BmaI1
Drug effect: Inhibits acyl-HSL synthase BmaI1 activity.
Max phase: Preclinical (in vitro)
Publication:
Christensen QH, et al., 2013. A high-throughput screen for quorum-sensing inhibitors that target acyl-homoserine lactone synthases. Proc Natl Acad Sci U S A 110(34):13815-20.