Drug details:
Molecular formula: C₂₅H₂₃ClN₂O₂

Standard name: 4-[(4-chlorophenyl)-(1-hydroxy-2-phenylindol-3-yl)methyl]morpholine

Synonyms:

3-[(4-chlorophenyl)(morpholin-4-yl)methyl]-2-phenyl-1H-indol-1-ol 4-[(4-chlorophenyl)-(1-hydroxy-2-phenylindol-3-yl)methyl]morpholine

Curated SMILES: C1COCCN1C(C2=CC=C(C=C2)Cl)C3=C(N(C4=CC=CC=C43)O)C5=CC=CC=C5

Evidence for compound's anti-virulence activity:

Burkholderia
Related VF: Quorum-sensing
Target: BmaI1
Drug effect: Inhibits acyl-HSL synthase BmaI1 activity.
Max phase: Preclinical (in vitro)
Publication:
Christensen QH, et al., 2013. A high-throughput screen for quorum-sensing inhibitors that target acyl-homoserine lactone synthases. Proc Natl Acad Sci U S A 110(34):13815-20.