Drug details:
Molecular formula: C₈H₇N

Standard name: 1H-indole

Synonyms:

1H-Indole 2,3-Benzopyrrole Indol 1-Benzazole Ketole 1-Azaindene Benzopyrrole 2,3-Benzopyrole Caswell No. 498B ......

Curated SMILES: C1=CC=C2C(=C1)C=CN2

Evidence for compound's anti-virulence activity:

Pseudomonas
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits a series of virulence factors such as quorum sensing, swarming and synthesis of pyocyanin, pyochelin and pyoverdine.
Max phase: Preclinical (in vivo)
Publication:
Lee J, et al., 2009. Indole and 7-hydroxyindole diminish Pseudomonas aeruginosa virulence. Microb Biotechnol 2(1):75-90.