Drug details:
Molecular formula: C₈H₇NO

Standard name: 1H-indol-7-ol

Synonyms:

1H-indol-7-ol 7-hydroxy indole 7-hydroxy-indole 7-hydroxyindole, AldrichCPR

Curated SMILES: C1=CC2=C(C(=C1)O)NC=C2

Evidence for compound's anti-virulence activity:

Pseudomonas
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits a series of virulence factors such as quorum sensing, swarming and synthesis of pyocyanin, pyochelin and pyoverdine.
Max phase: Preclinical (in vivo)
Publication:
Lee J, et al., 2009. Indole and 7-hydroxyindole diminish Pseudomonas aeruginosa virulence. Microb Biotechnol 2(1):75-90.