Drug details:
Molecular formula: C₁₁H₈N₂

Standard name: 9H-pyrido[3,4-b]indole

Synonyms:

9H-Pyrido[3,4-B]indole Norharman beta-Carboline 2,9-Diazafluorene Carbazoline 9H-Beta-carboline 2-Azacarbazole 2H-Pyrido[3,4-b]indole .beta.-Carboline ......

Curated SMILES: C1=CC=C2C(=C1)C3=C(N2)C=NC=C3

Evidence for compound's anti-virulence activity:

Escherichia
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits biofilm formation and reduces fimbriae production and swarming and swimming motilities.
Max phase: Preclinical (in vivo)
Publication:
Lee JH, et al., 2017. Antibiofilm activities of norharmane and its derivatives against Escherichia coli O157:H7 and other bacteria. Phytomedicine 36:254-261.

Pseudomonas
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits biofilm formation.
Max phase: Preclinical (in vitro)
Publication:
Lee JH, et al., 2017. Antibiofilm activities of norharmane and its derivatives against Escherichia coli O157:H7 and other bacteria. Phytomedicine 36:254-261.