Drug details:
Molecular formula: C₁₇H₁₅ClN₂

Standard name: 5,11-dimethyl-6H-pyrido[4,3-b]carbazole;hydrochloride

Synonyms:

Ellipticine HCl 5,11-dimethyl-6H-pyrido[4,3-b]carbazole hydrochloride Ellipticine (hydrochloride) 5,11-Dimethyl-6H-pyrido(4,3-b)carbazole hydrochloride Ellipticinehydrochloride 6H-Pyrido(4,3-b)carbazole, 5,11-dimethyl-, hydrochloride NSC71795 hydrochloride NSC 71795 (hydrochloride) 5,11-dimethyl-6H-pyrido[4,3-b]carbazole hydrochloride

Curated SMILES: CC1=C2C=CN=CC2=C(C3=C1NC4=CC=CC=C43)C.Cl

Evidence for compound's anti-virulence activity:

Streptococcus
Related VF: Suilysin
Target: Sly
Drug effect: Directly binds to Suilysin to interfere with the hemolytic activity.
Max phase: Preclinical (in vivo)
Publication:
Wang C, et al., 2021. Effective Antibacterial and Antihemolysin Activities of Ellipticine Hydrochloride against Streptococcus suis in a Mouse Model. Appl Environ Microbiol 87(10):e03165-20.