Drug details:
Classification: Phenethylamines; Benzene and substituted derivatives; Benzenoids; Organic compounds;

Curated SMILES: CN(CC1=CSC=C1)CC1CCN(CCC2=CC=C(C3=CC=CC=C3)C=C2)CC1

Evidence for compound's anti-virulence activity:

Salmonella
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits biofilm formation and disrupts preformed biofilms.
Max phase: Preclinical (in vivo)
Publication:
Woolard KJ, et al., 2022. Development of small molecules that work cooperatively with ciprofloxacin to clear salmonella biofilms in a chronic gallbladder carriage model. Eur J Med Chem 232:114203.