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(5R,6R)-5,6-bis[(4-tert-butyltriazol-1-yl)methyl]-4,5,6,7-tetrahydro-1H-benzimidazol-2-amine

Drug details:
Molecular formula: C21H33N9

Classification: Imidazoles; Azoles; Organoheterocyclic compounds; Organic compounds;
Chemical structure:
Depiction based on curated SMILES N N N H 2 N HN N N H 3 C CH 3 H 3 C N CH 3 H H N CH 3 H 3 C

Evidence for compound's anti-virulence activity:

Acinetobacter
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits biofilm formation.
Max phase: Preclinical (in vitro)
Publication:
Huigens RW 3rd, et al., 2009. Inhibition of Acinetobacter baumannii, Staphylococcus aureus and Pseudomonas aeruginosa biofilm formation with a class of TAGE-triazole conjugates. Org Biomol Chem 7(4):794-802.

Staphylococcus
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits biofilm formation.
Max phase: Preclinical (in vitro)
Publication:
Huigens RW 3rd, et al., 2009. Inhibition of Acinetobacter baumannii, Staphylococcus aureus and Pseudomonas aeruginosa biofilm formation with a class of TAGE-triazole conjugates. Org Biomol Chem 7(4):794-802.








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