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Compound category: Imidazoles
(total 62 related compounds in database, current show from 1 to 10)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
N-[4-(1-hydroxy-6-nitrobenzimidazol-2-yl)phenyl]-4-(1,3-oxazol-5-yl)benzamide Depiction based on curated SMILES HO N N + N O _ O N H O O N Yersinia TTSS (Type III secretion system) Preclinical (in vivo) Garrity-Ryan LK, et al. 2010. Infect Immun
6-(3H-benzimidazol-5-yl)-3-pyridin-4-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole Depiction based on curated SMILES N N N N HN S N N Staphylococcus Others Preclinical (in vivo) Zhang J, et al. 2014. Proc Natl Acad Sci U S A
(5R,6R)-5,6-bis[(4-benzyltriazol-1-yl)methyl]-4,5,6,7-tetrahydro-1H-benzimidazol-2-amine Depiction based on curated SMILES N H N N N N N H N H N H 2 N Acinetobacter
Pseudomonas		 Biofilm
Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Huigens RW 3rd, et al. 2009. Org Biomol Chem
5beta,6alpha-Bis(4-butyl-1H-1,2,3-triazole-1-ylmethyl)-4,5,6,7-tetrahydro-1H-benzoimidazole-2-amine Depiction based on curated SMILES N N N H 2 N N H N N H 3 C N H 3 C H H N Acinetobacter Biofilm Preclinical (in vitro) Huigens RW 3rd, et al. 2009. Org Biomol Chem
5beta,6alpha-Bis(4-heptyl-1H-1,2,3-triazole-1-ylmethyl)-4,5,6,7-tetrahydro-1H-benzoimidazole-2-amine Depiction based on curated SMILES H 3 C N N N HN H 2 N N N N N H 3 C H H Acinetobacter
Pseudomonas		 Biofilm
Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Huigens RW 3rd, et al. 2009. Org Biomol Chem
5beta,6alpha-Bis(4-hexyl-1H-1,2,3-triazole-1-ylmethyl)-4,5,6,7-tetrahydro-1H-benzoimidazole-2-amine Depiction based on curated SMILES H 3 C N N N N H H 2 N N N N N H 3 C H H Acinetobacter
Pseudomonas		 Biofilm
Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Huigens RW 3rd, et al. 2009. Org Biomol Chem
5beta,6alpha-Bis(4-pentyl-1H-1,2,3-triazole-1-ylmethyl)-4,5,6,7-tetrahydro-1H-benzoimidazole-2-amine Depiction based on curated SMILES N N H 3 C N HN H 2 N N N N N H 3 C H H Acinetobacter
Pseudomonas		 Biofilm
Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Huigens RW 3rd, et al. 2009. Org Biomol Chem
(5R,6R)-5,6-bis[(4-tert-butyltriazol-1-yl)methyl]-4,5,6,7-tetrahydro-1H-benzimidazol-2-amine Depiction based on curated SMILES N N N H 2 N HN N N H 3 C CH 3 H 3 C N CH 3 H H N CH 3 H 3 C Acinetobacter
Staphylococcus		 Biofilm
Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Huigens RW 3rd, et al. 2009. Org Biomol Chem
(5R,6R)-5,6-bis[[4-(2-phenylethyl)triazol-1-yl]methyl]-4,5,6,7-tetrahydro-1H-benzimidazol-2-amine Depiction based on curated SMILES N H N N N N NH N H N NH 2 Acinetobacter
Pseudomonas
Staphylococcus		 Biofilm
Biofilm
Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)
Preclinical (in vitro)		 Huigens RW 3rd, et al. 2009. Org Biomol Chem
(5R,6R)-5,6-bis[[4-(3-methylbutyl)triazol-1-yl]methyl]-4,5,6,7-tetrahydro-1H-benzimidazol-2-amine Depiction based on curated SMILES N N H 3 C CH 3 N N H H 2 N N N N CH 3 N H 3 C H H Acinetobacter
Pseudomonas		 Biofilm
Biofilm		 Preclinical (in vitro)
Preclinical (in vitro)		 Huigens RW 3rd, et al. 2009. Org Biomol Chem
   


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