Drug details:
Molecular formula: C₂₃H₁₅N₅O₅

Standard name: N-[4-(1-hydroxy-6-nitrobenzimidazol-2-yl)phenyl]-4-(1,3-oxazol-5-yl)benzamide

Curated SMILES: C1=CC(=CC=C1C2=CN=CO2)C(=O)NC3=CC=C(C=C3)C4=NC5=C(N4O)C=C(C=C5)[N+](=O)[O-]

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS (Type III secretion system)
Target: VirF/LcrF
Drug effect: Targets the conserved DNA-binding domain of LcrF.
Max phase: Preclinical (in vivo)
Publication:
Garrity-Ryan LK, et al., 2010. Small molecule inhibitors of LcrF, a Yersinia pseudotuberculosis transcription factor, attenuate virulence and limit infection in a murine pneumonia model. Infect Immun 78(11):4683-90.