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Compound category: Imidazoles
(total 62 related compounds in database, current show from 51 to 60)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
N-(4-methylphenyl)-2-[(5-nitro-1H-benzimidazol-2-yl)sulfanyl]acetamide Depiction based on curated SMILES N H _ O O + N CH 3 N S O N H Pseudomonas Biofilm Preclinical (in vitro) Starkey M, et al. 2014. PLoS Pathog
N-[3-(2-amino-1H-imidazol-5-yl)phenyl]heptanamide;hydrochloride Depiction based on curated SMILES ClH NH 2 N H N H 3 C HN O Pseudomonas Biofilm Preclinical (in vitro) Bunders CA, et al. 2010. Bioorg Med Chem Lett
Heptanoic acid [4-(2-amino-3H-imidazol-4-yl)phenyl]amide hydrochloride Depiction based on curated SMILES ClH H 2 N N H N H 3 C N H O Pseudomonas Biofilm Preclinical (in vitro) Bunders CA, et al. 2010. Bioorg Med Chem Lett
Fenbendazole Depiction based on curated SMILES S CH 3 N H N N H O O Salmonella Invasion Preclinical (in vitro) Ridge Y, et al. 2018. J Appl Microbiol
N-[2-[4-(benzimidazol-1-yl)anilino]-2-oxoethyl]-3-chloro-1-benzothiophene-2-carboxamide Depiction based on curated SMILES N H N N O S Cl O N H Salmonella
Yersinia
TTSS (SPI-1 encode)
TTSS (Type III secretion system)
Preclinical (in vitro)
Preclinical (in vivo)
Boonyom R, et al. 2022. J Genet Eng Biotechnol
Swietnicki W, et al. 2011. PLoS One
5-Chloro-2-phenoxymethyl-1H-benzoimidazole Depiction based on curated SMILES O Cl N H N Shigella VirF Preclinical (in vitro) Emanuele AA, et al. 2014. J Antibiot (Tokyo); Emanuele AA, et al. 2015. PLoS One
3-(5-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)propan-1-ol Depiction based on curated SMILES N H F F F OH N Vibrio Post-translational modification Preclinical (in vitro) Wang G, et al. 2022. ChemMedChem
Isonaamine A Depiction based on curated SMILES HO N H 2 N OH N Vibrio Biofilm Preclinical (in vitro) Mai T, et al. 2015. Lett Appl Microbiol
Isonaamine D Depiction based on curated SMILES N HO H 2 N N CH 3 O Vibrio Biofilm Preclinical (in vitro) Mai T, et al. 2015. Lett Appl Microbiol
Benzimidazole 2
(internal name in literature)
Depiction based on curated SMILES N H F F F OH Cl N Vibrio Post-translational modification Preclinical (in vitro) Wang G, et al. 2022. ChemMedChem
   


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