Drug details:
Molecular formula: C₁₅H₁₀O₆

Standard name: 2-(3,4-dihydroxyphenyl)-3,7-dihydroxychromen-4-one

Synonyms:

5-Desoxyquercetin 2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-chromen-4-one 3,3',4',7-Tetrahydroxyflavone Cotinin Fustel Viset Fisetholz Superfustel Fietin ......

Curated SMILES: O=C1C(O)=C(C2=CC(O)=C(O)C=C2)OC2=C1C=CC(O)=C2

Evidence for compound's anti-virulence activity:

Acinetobacter
Related VF: BfmRS
Target: BfmR
Drug effect: Binds to BfmR, a response regulator that is the master controller of biofilm formation.
Max phase: Preclinical (in vitro)
Publication:
Raorane CJ, et al., 2019. Antibiofilm and Antivirulence Efficacies of Flavonoids and Curcumin Against Acinetobacter baumannii. Front Microbiol 10:990.

Klebsiella
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits formation of curli.
Max phase: Preclinical (in vitro)
Publication:
Adeosun IJ, et al., 2022. Anti-Biofilm and Associated Anti-Virulence Activities of Selected Phytochemical Compounds against Klebsiella pneumoniae. Plants (Basel) 11(11):1429.