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Compound category: Flavones
(total 10 related compounds in database)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
Kaempferol Depiction based on curated SMILES OH OH O O HO HO Listeria
Streptococcus
LLO (Listeriolysin O)
Pneumolysin
Preclinical (in vivo)
Preclinical (in vivo)
Wang T, et al. 2022. Microbiol Spectr
Xu L, et al. 2023. Microbes Infect
Baicalein Depiction based on curated SMILES HO HO OH O O Listeria LLO (Listeriolysin O) Preclinical (in vivo) Wang J, et al. 2015. Sci Rep; Lu G, et al. 2019. J Cell Mol Med
Fisetin Depiction based on curated SMILES HO OH O O HO HO Acinetobacter
Klebsiella
BfmRS
Biofilm
Preclinical (in vitro)
Preclinical (in vitro)
Raorane CJ, et al. 2019. Front Microbiol
Adeosun IJ, et al. 2022. Plants (Basel)
Luteolin Depiction based on curated SMILES HO HO OH OH O O Aeromonas Aerolysin Preclinical (in vitro) Dong J, et al. 2021. Virulence
4',5-Dihydroxyflavone Depiction based on curated SMILES OH HO O O Clostridium Collagenase Preclinical (in vitro) Nitulescu G, et al. 2022. Life (Basel)
Quercetin Depiction based on curated SMILES OH OH OH OH HO O O Enterococcus Biofilm Preclinical (in vitro) Qayyum S, et al. 2019. Microb Pathog
Myricetin Depiction based on curated SMILES HO OH OH O O OH HO HO Helicobacter
Listeria
Staphylococcus
Biofilm
LLO (Listeriolysin O)
Others; Adherence; Biofilm
Preclinical (in vitro)
Preclinical (in vitro)
Preclinical (in vitro)
Krzyzek P, et al. 2021. Int J Mol Sci
Wang J, et al. 2015. Sci Rep
Hu P, et al. 2021. Int J Med Microbiol
Morin Depiction based on curated SMILES O OH OH HO O HO OH Listeria LLO (Listeriolysin O) Preclinical (in vitro) Wang J, et al. 2015. Sci Rep
Chrysin Depiction based on curated SMILES O OH HO O Listeria LLO (Listeriolysin O) Preclinical (in vitro) Wang J, et al. 2015. Sci Rep
3,5-dichloro-N-[2-(2-chlorophenyl)-5-hydroxy-4-oxo-4H-chromen-8-yl]-2-hydroxybenzenesulfonamide Depiction based on curated SMILES O HO OH Cl Cl O O S N H O Cl Salmonella TTSS (SPI-2 encode) Preclinical (in vitro) El Qaidi S, et al. 2018. Front Cell Infect Microbiol
   


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