Drug details:
Molecular formula: C₁₅H₁₀O₄

Standard name: 5-hydroxy-2-(4-hydroxyphenyl)chromen-4-one

Synonyms:

5,4'-Dihydroxyflavone 5-Hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one 5-hydroxy-2-(4-hydroxyphenyl)chromen-4-one 5,4''-dihydroxyflavone 4H-1-Benzoicpyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)- 5,4''''-Dihydroxyflavone 5,4-DIHYDROXYFLAVONE 4',5-Dihydroxyflavone, 95% 4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-

Curated SMILES: C1=CC(=C2C(=C1)OC(=CC2=O)C3=CC=C(C=C3)O)O

Evidence for compound's anti-virulence activity:

Clostridium
Related VF: Collagenase
Target: ColA
Drug effect: Inhibits collagenase activity to block the colonization and infiltration of the host by the bacteria.
Max phase: Preclinical (in vitro)
Publication:
Nitulescu G, et al., 2022. Discovery of New Microbial Collagenase Inhibitors. Life (Basel) 12(12):2114.