Drug details:
Molecular formula: C₁₅H₁₀O₄

Standard name: 5,7-dihydroxy-2-phenylchromen-4-one

Synonyms:

5,7-Dihydroxyflavone 5,7-Dihydroxy-2-phenyl-4H-chromen-4-one Chrysine 5,7-dihydroxy-2-phenylchromen-4-one Crysin 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-phenyl- FLAVONE, 5,7-DIHYDROXY- 5,7-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one EINECS 207-549-7 ......

Curated SMILES: C1=CC=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O

Evidence for compound's anti-virulence activity:

Listeria
Related VF: LLO (Listeriolysin O)
Target: Hly
Drug effect: Inhibits the activity of LLO.
Max phase: Preclinical (in vitro)
Publication:
Wang J, et al., 2015. Novel inhibitor discovery and the conformational analysis of inhibitors of listeriolysin O via protein-ligand modeling. Sci Rep 5:8864.