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4-phenyl-1,4-dihydroindeno[1,2-d][1,3]thiazine-2,5-dione

Drug details:
Molecular formula: C17H11NO2S

Classification: Indenes and isoindenes; Benzenoids; Organic compounds;
Chemical structure:
Depiction based on curated SMILES S O O HN

Evidence for compound's anti-virulence activity:

Pseudomonas
Related VF: TTSS (Type III secretion system)
Target: Not determined
Drug effect: Blocks translocation of effectors into host cells.
Max phase: Preclinical (in vitro)
Publication:
Harmon DE, et al., 2010. Identification and characterization of small-molecule inhibitors of Yop translocation in Yersinia pseudotuberculosis. Antimicrob Agents Chemother 54(8):3241-54.








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