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furo[3,2-b]quinoxalin-3-yl-(4-phenylpiperazin-1-yl)methanone

Drug details:
Molecular formula: C21H18N4O2

Classification: Piperazines; Diazinanes; Organoheterocyclic compounds; Organic compounds;
Chemical structure:
Depiction based on curated SMILES N N N O N O

Evidence for compound's anti-virulence activity:

Pseudomonas
Related VF: TTSS (Type III secretion system)
Target: Not determined
Drug effect: Blocks translocation of effectors into host cells.
Max phase: Preclinical (in vitro)
Publication:
Harmon DE, et al., 2010. Identification and characterization of small-molecule inhibitors of Yop translocation in Yersinia pseudotuberculosis. Antimicrob Agents Chemother 54(8):3241-54.








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