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2-{[5-(4-chlorophenyl)-1H-imidazol-2-yl]thio}-N-(3-ethoxyphenyl)acetamide

Drug details:
Molecular formula: C19H18ClN3O2S

Classification: Imidazoles; Azoles; Organoheterocyclic compounds; Organic compounds;
Chemical structure:
Depiction based on curated SMILES N H Cl N H 3 C S O N H O

Evidence for compound's anti-virulence activity:

Pseudomonas
Related VFcategory: Biofilm
Target: MvfR
Drug effect: Inhibits MvfR-regulated virulence functions.
Max phase: Preclinical (in vitro)
Publication:
Starkey M, et al., 2014. Identification of anti-virulence compounds that disrupt quorum-sensing regulated acute and persistent pathogenicity. PLoS Pathog 10(8):e1004321.








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