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Capsaicin

Drug details:
Molecular formula: C18H27NO3

Classification: Methoxyphenols; Phenols; Benzenoids; Organic compounds;
Synonyms:  Zostrix
(E)-Capsaicin
Qutenza
Axsain
Styptysat
Isodecenoic acid vanillylamide
Ausanil
trans-Capsaicin
trans-8-Methyl-N-vanillyl-6-nonenamide
......

Chemical structure:
Depiction based on curated SMILES HN CH 3 O OH H 3 C O CH 3

Evidence for compound's anti-virulence activity:

Clostridium
Related VF: Collagenase
Target: ColA
Drug effect: Inhibits collagenase activity to block the colonization and infiltration of the host by the bacteria.
Max phase: Preclinical (in vitro)
Publication:
Nitulescu G, et al., 2022. Discovery of New Microbial Collagenase Inhibitors. Life (Basel) 12(12):2114.








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