Vibrio
Related VF: HlyU
Target: HlyU
Drug effect: Inhibits the transcription of the highly invasive repeat-in-toxin (rtxA1) and hemolysin (vvhA) along with other HlyU regulated virulence genes.
Max phase: Preclinical (in vivo)
Publication: Imdad S, et al., 2018. Identification and Validation of an Antivirulence Agent Targeting HlyU-Regulated Virulence in Vibrio vulnificus. Front Cell Infect Microbiol 8:152.