Drug details:
Molecular formula: C₁₈H₁₉ClF₃N₅

Standard name: N-[3-(4-chlorophenyl)-5-methyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]-N',N'-dimethylethane-1,2-diamine

Synonyms:

N'-[3-(4-chlorophenyl)-5-methyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl]-N,N-dimethylethane-1,2-diamine N1-(3-(4-chlorophenyl)-5-methyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-yl)-N2,N2-dimethylethane-1,2-diamine

Curated SMILES: CC1=NC2=C(C(=NN2C(=C1)NCCN(C)C)C(F)(F)F)C3=CC=C(C=C3)Cl

Evidence for compound's anti-virulence activity:

Vibrio
Related VFcategory: Stress survival
Target: Not determined
Drug effect: Inhibits σE stress response pathway of Vibrio cholerae that is required for full virulence of the organism.
Max phase: Preclinical (in vitro)
Publication:
Stanbery L, et al., 2017. Assay development and high-throughput screening for small molecule inhibitors of a Vibrio cholerae stress response pathway. Drug Des Devel Ther 11:2777-2785.