|
(4-chloro-2-methyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-3-yl)methyl imidothiocarbamate |
|
Helicobacter |
Flagella |
Preclinical (in vivo) |
Suerbaum S, et al. 2022. mBio |
|
(4-bromo-2-methyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-3-yl)methyl imidothiocarbamate |
Depiction based on curated SMILES
H
2
N
NH
S
Br
H
3
C
N
O
N
|
Helicobacter |
Flagella |
Preclinical (in vitro) |
Suerbaum S, et al. 2022. mBio |
|
1-{(E)-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)imino]methyl}naphthalen-2-ol |
Depiction based on curated SMILES
N
OH
H
3
C
CH
3
N
N
|
Pseudomonas Yersinia |
TTSS (Type III secretion system) TTSS (Type III secretion system) |
Preclinical (in vitro) Preclinical (in vitro) |
Harmon DE, et al. 2010. Antimicrob Agents Chemother
|
|
5-methyl-2-phenyl-4-[(2,4,6-tribromophenyl)iminomethyl]-1H-pyrazole-3-thione |
Depiction based on curated SMILES
Br
Br
Br
N
CH
3
HN
N
S
|
Staphylococcus |
Others |
Preclinical (in vitro) |
Suree N, et al. 2009. Bioorg Med Chem |
|
5-methyl-4-{[(4-nitrophenyl)amino]methylene}-2-phenyl-2,4-dihydro-3H-pyrazole-3-thione |
Depiction based on curated SMILES
_
O
O
+
N
N
H
H
3
C
S
N
N
|
Staphylococcus |
Others |
Preclinical (in vitro) |
Suree N, et al. 2009. Bioorg Med Chem |
|
3-(4-CHLOROPHENYL)-N-[2-(DIMETHYLAMINO)ETHYL]-5-METHYL-2-(TRIFLUOROMETHYL)PYRAZOLO[1,5-A]PYRIMIDIN-7-AMINE |
Depiction based on curated SMILES
N
Cl
F
F
F
CH
3
CH
3
CH
3
N
H
N
N
N
|
Vibrio |
Stress survival |
Preclinical (in vitro) |
Stanbery L, et al. 2017. Drug Des Devel Ther |
|
2-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)iminoindene-1,3-dione |
Depiction based on curated SMILES
H
3
C
N
N
O
O
H
3
C
O
N
|
Yersinia |
TTSS secreted effectors |
Preclinical (in vitro) |
Hu X, et al. 2013. Bioorg Med Chem Lett |
|
5-[3'-(4-methylphenyl)-1'-phenyl-5-(2-thienyl)-3,4-dihydro-1'H,2H-3,4'-bipyrazol-2-yl]-5-oxopentanoic acid |
Depiction based on curated SMILES
O
S
N
N
O
OH
N
N
CH
3
|
Yersinia |
TTSS (Type III secretion system) |
Preclinical (in vitro) |
Pan NJ, et al. 2009. Antimicrob Agents Chemother |
|
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