Drug details:
Molecular formula: C₂₈H₂₆N₄O₃S

Standard name: 5-[3-[3-(4-methylphenyl)-1-phenylpyrazol-4-yl]-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]-5-oxopentanoic acid

Synonyms:

5-[3'-(4-methylphenyl)-1'-phenyl-5-(thiophen-2-yl)-3,4-dihydro-1'H,2H-3,4'-bipyrazol-2-yl]-5-oxopentanoic acid 5-[3'-(4-methylphenyl)-1'-phenyl-5-thien-2-yl-3,4-dihydro-1'H,2H-3,4'-bipyrazol-2-yl]-5-oxopentanoic acid

Curated SMILES: CC1=CC=C(C2=NN(C3=CC=CC=C3)C=C2C2CC(C3=CC=CS3)=NN2C(=O)CCCC(=O)O)C=C1

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS (Type III secretion system)
Target: Not determined
Drug effect: Inhibits translocation of Yop effectors.
Max phase: Preclinical (in vitro)
Publication:
Pan NJ, et al., 2009. Targeting type III secretion in Yersinia pestis. Antimicrob Agents Chemother 53(2):385-92.