Drug details:
Molecular formula: C₁₂H₁₃ClN₄OS

Standard name: (4-chloro-2-methyl-5-oxo-1-phenylpyrazol-3-yl)methyl carbamimidothioate

Synonym:

(4-chloro-2-methyl-5-oxo-1-phenylpyrazol-3-yl)methyl carbamimidothioate

Curated SMILES: CN1C(=C(C(=O)N1C2=CC=CC=C2)Cl)CSC(=N)N

Evidence for compound's anti-virulence activity:

Helicobacter
Related VF: Flagella
Target: Not determined
Drug effect: Inhibits motility and flagellar assembly.
Max phase: Preclinical (in vivo)
Publication:
Suerbaum S, et al., 2022. Identification of Antimotilins, Novel Inhibitors of Helicobacter pylori Flagellar Motility That Inhibit Stomach Colonization in a Mouse Model. mBio 13(2):e0375521.