Drug details:
Molecular formula: C₂₀H₁₅N₃O₃

Standard name: 2-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)iminoindene-1,3-dione

Synonyms:

2-[(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)imino]indene-1,3-dione 2-(1,5-dimethyl-3-oxidanylidene-2-phenyl-pyrazol-4-yl)iminoindene-1,3-dione 2-[(3-keto-1,5-dimethyl-2-phenyl-3-pyrazolin-4-yl)imino]indane-1,3-quinone Indan-1,3-dione, 2-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylimino)- 2-[(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)imino]-1H-indene-1,3(2H)-dione

Curated SMILES: CC1=C(N=C2C(=O)C3=CC=CC=C3C2=O)C(=O)N(C2=CC=CC=C2)N1C

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: Preclinical (in vitro)
Publication:
Hu X, et al., 2013. Inhibitors of the Yersinia protein tyrosine phosphatase through high throughput and virtual screening approaches. Bioorg Med Chem Lett 23(4):1056-62.