Drug details:
Molecular formula: C₂₄H₁₉N₃O₅

Standard name: ethyl 4-[3-(furan-2-yl)-4-(4-hydroxyphenyl)-6-oxo-2,4-dihydropyrrolo[3,4-c]pyrazol-5-yl]benzoate

Synonyms:

C390-0497 ethyl 4-[3-(furan-2-yl)-4-(4-hydroxyphenyl)-6-oxo-2,4-dihydropyrrolo[3,4-c]pyrazol-5-yl]benzoate

Curated SMILES: CCOC(=O)C1=CC=C(C=C1)N2C(C3=C(NN=C3C2=O)C4=CC=CO4)C5=CC=C(C=C5)O

Evidence for compound's anti-virulence activity:

Vibrio
Related VFcategory: Stress survival
Target: Not determined
Drug effect: Inhibits σE stress response pathway of Vibrio cholerae that is required for full virulence of the organism.
Max phase: Preclinical (in vitro)
Publication:
Stanbery L, et al., 2017. Assay development and high-throughput screening for small molecule inhibitors of a Vibrio cholerae stress response pathway. Drug Des Devel Ther 11:2777-2785.