Drug details:
Molecular formula: C₂₃H₂₀N₂O₅S₂

Standard name: N-[8-hydroxy-7-(4-methylphenyl)sulfonylquinolin-5-yl]-4-methylbenzenesulfonamide

Synonym:

N-{8-hydroxy-7-[(4-methylphenyl)sulfonyl]quinolin-5-yl}-4-methylbenzenesulfonamide

Curated SMILES: CC1=CC=C(C=C1)S(=O)(=O)C2=C(C3=C(C=CC=N3)C(=C2)NS(=O)(=O)C4=CC=C(C=C4)C)O

Evidence for compound's anti-virulence activity:

Vibrio
Related VFcategory: Stress survival
Target: Not determined
Drug effect: Inhibits σE stress response pathway of Vibrio cholerae that is required for full virulence of the organism.
Max phase: Preclinical (in vitro)
Publication:
Stanbery L, et al., 2017. Assay development and high-throughput screening for small molecule inhibitors of a Vibrio cholerae stress response pathway. Drug Des Devel Ther 11:2777-2785.