Drug details:
Molecular formula: C₂₃H₁₈N₄O₃S₂

Standard name: N-[4-(2-oxo-3,4-dihydro-1H-quinolin-6-yl)-1,3-thiazol-2-yl]-3-(1,3-thiazol-4-ylmethoxy)benzamide

Curated SMILES: O=C1CCC2=C(C=CC(C3=CSC(NC(=O)C4=CC=CC(OCC5=CSC=N5)=C4)=N3)=C2)N1

Evidence for compound's anti-virulence activity:

Shigella
Related VF: TTSS (Type III secretion system)
Target: Spa47
Drug effect: Inhibits T3SS ATPase.
Max phase: Preclinical (in vitro)
Publication:
Case HB, et al., 2018. Shutting Down Shigella Secretion: Characterizing Small Molecule Type Three Secretion System ATPase Inhibitors. Biochemistry 57(50):6906-6916.