Quinolones and derivatives (total related compounds in database) |
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7-[4-[(R)-hydroxy-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]-3-methylphenyl]-2H-isoquinolin-1-one |
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Escherichia |
Type 1 fimbriae |
Preclinical (in vivo) |
Mydock-McGrane L, et al. 2016. J Med Chem |
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7-[4-[(R)-hydroxy-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]-3-methylphenyl]-3,4-dihydro-2H-isoquinolin-1-one |
Depiction based on curated SMILES
HO
OH
OH
OH
O
HO
H
CH
3
O
N
H
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Escherichia |
Type 1 fimbriae |
Preclinical (in vivo) |
Mydock-McGrane L, et al. 2016. J Med Chem |
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Virstatin |
Depiction based on curated SMILES
O
HO
O
N
O
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Acinetobacter Vibrio |
TFP (Type IV pili) TCP (Toxin-coregulated pilus) |
Preclinical (in vitro) Preclinical (in vivo) |
Nait Chabane Y, et al. 2014. BMC Microbiol Hung DT, et al. 2005. Science |
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1'-butyl-4'-(nitromethyl)-1',4'-dihydro-2,3'-biquinoline |
Depiction based on curated SMILES
_
O
O
+
N
H
3
C
N
N
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Shigella |
VirF |
Preclinical (in vitro) |
Koppolu V, et al. 2013. Infect Immun |
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N-[4-(2-oxo-3,4-dihydro-1H-quinolin-6-yl)-1,3-thiazol-2-yl]-3-(1,3-thiazol-4-ylmethoxy)benzamide |
Depiction based on curated SMILES
N
H
N
N
S
O
O
O
N
H
S
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Shigella |
TTSS (Type III secretion system) |
Preclinical (in vitro) |
Case HB, et al. 2018. Biochemistry |
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