Drug details:
Molecular formula: C₂₀H₁₆N₄O₄

Standard name: N-(furan-2-ylmethylcarbamoyl)-2-(4-oxobenzo[g]quinazolin-3-yl)acetamide

Curated SMILES: O=C(CN1C=NC2=CC3=CC=CC=C3C=C2C1=O)NC(=O)NCC1=CC=CO1

Evidence for compound's anti-virulence activity:

Shigella
Related VF: TTSS (Type III secretion system)
Target: Spa47; IpaC
Drug effect: Inhibits transcriptional activator.
Max phase: Preclinical (in vivo)
Publication:
Case HB, et al., 2020. Novel Noncompetitive Type Three Secretion System ATPase Inhibitors Shut Down Shigella Effector Secretion. Biochemistry 59(28):2667-2678.